Catalent, the leading global provider of advanced delivery technologies, development, and manufacturing solutions for drugs, biologics, cell and gene therapies, and consumer health products, and Delphi Genetics, a plasmid DNA (pDNA) cell and gene therapy contract development and manufacturing organization (CDMO) based in Gosselies, Belgium, today announced that they have […]
Cancer cells can experience stress. They have to contend with attacks by the immune system or with anti-cancer therapeutics. If they attempt to colonize other tissues, they have to break away from the extracellular matrix, enter the bloodstream and survive during the travel through the body. Then exit and start […]
A new study from UCLA and Stanford University researchers finds that three-dimensional human stem cell-derived 'mini brain' organoids can mature in a manner that is strikingly similar to human brain development. For the new study, published in Nature Neuroscience February 22, senior authors Dr. Daniel Geschwind of UCLA and Dr. […]
Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique (INRS) has identified a therapeutic approach to restore the effectiveness of immune cells. The study, led by doctoral student Hamza Loucif and Professor […]
Researchers at the University of Massachusetts Amherst have gained new insight into the biological processes of a chytrid fungus responsible for a deadly skin infection devastating frog populations worldwide. Led by cell biologist Lillian Fritz-Laylin, the team describes in a paper published Feb. 8 in Current Biology how the actin […]
A process that releases iron in response to stress may contribute to heart failure, and blocking this process could be a way of protecting the heart, suggests a study in mice published today in eLife. People with heart failure often have an iron deficiency, leading some scientists to suspect that […]
Keratoacanthoma is a benign skin cancer characterised by small dome-like bumps on the surface of the skin. Credit: Maridav/Shutterstock.com Keratoacanthoma originates in the hair follicle and is not known to spread. It is very similar to the Squamous Cell Carcinoma (SCC). However, this is a much more aggressive type of […]
One of the most fundamental differences between animal and plant cells is the cell wall – a rigid structure surrounding the plant cells. The cell wall provides strength and structural support, but it also hinders the plant cells from being in direct contact with one another. To overcome this, plants […]
Sepsis is a potentially fatal condition brought on by the body’s exaggerated reaction to an infection. It can be caused by common infections, such as influenza, by bacteria, virus, fungi and sometimes parasites. Lactate is a by-product of cellular respiration and is often elevated in sepsis. However, how exactly the […]
Giant cell arteritis (GCA), along with polymyalgia rheumatica (PMR), are autoimmune disorders involving the medium and large arteries which have muscular walls and vasa vasorum in their adventitial coats. What is GCA? GCA is one form of vascular inflammatory disorder that affects the large aortic branches, especially those of the […]