SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a primarily respiratory virus. It is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. In severe or critical cases, however, this virus is known to trigger rapid and severe deterioration of multiple organs, including the central nervous system. […]

Research looks at SARS-CoV-2 transmission from people to pets

A large team of researchers from the US demonstrated that pets with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely acquired the putative virus from humans.  This suggests that human-animal infection may actually occur much more frequently than previously thought – implying that infected individuals should limit their contact […]

Statins improve 28-day mortality in hospitalized COVID-19 patients

Amid the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), people with comorbidities are at a higher risk of developing severe disease. In the fight against COVID-19, scientists are racing to determine effective treatments to reduce mortality among infected individuals. Now, researchers at Harvard Medical […]

Mouse monoclonal antibodies protect against SARS-CoV-2 wildtype, UK and South African variants

The importance of cross-neutralizing antibodies to the recently emerged variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is evident in light of the fact that these variants are highly transmissible as well as being able to evade immune responses to earlier variants of this virus. A new preprint […]

Novel polyclonal antibody XAV-19 efficiently neutralizes UK and South African SARS-CoV-2 variants

A promising new study, released as a preprint on the bioRxiv* server, reports on the high neutralizing efficacy of a polyclonal swine antibody against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the novel coronavirus disease 2019 (COVID-19). By demonstrating the ability of this antibody to […]

CAL20.C SARS-CoV-2 variant skyrocketing in California evades host immune response

The effect of different neutralizing antibodies, both vaccine-elicited and from convalescent sera, suggests new variants are emerging that can evade the human immune response. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to host cells via its spike protein, which has two parts, the S1 and S2 subunits. The […]

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

As the coronavirus disease (COVID-19) pandemic continues, scientists race to develop or find effective treatments to stem its spread. At the same time, health experts and scientists continue to determine which existing drugs could be repurposed to treat COVID-19. Researchers at the University of Hong Kong found that Clofazimine, a […]