Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), resides in mucous membranes, making it easy to detect viral load in the nasal cavities. An international group of researchers has characterized the immunological and diagnosis characteristics of patients who may have or are confirmed […]
Using Phage Display for Antibody Discovery and Development
In phage-display, a gene encoding the surface protein of a bacteriophage is replaced with a gene encoding a novel protein. The technique can be used in drug discovery and research for the investigation of novel polypeptides. Image Credit: Axel_Kock / Shutterstock.com The discovery of phage display was spurred on by […]
SARS-CoV-2 antibody test helps select donor blood samples for therapeutic use
Researchers have developed and applied a robust, versatile antibody test to assist health authorities in managing the coronavirus disease 2019 (COVID-19) pandemic, according to a study published January 14 in the open-access journal PLOS Pathogens by Andrea Gamarnik of the Fundación Instituto Leloir-CONICET in Argentina, and colleagues. As of November […]
Oxford vaccine stimulates broad antibody and T cell functions
Today, researchers from the University of Oxford have published further data from the Phase I/II clinical trials of the ChAdOx1 nCoV-19 coronavirus vaccine, evidencing the decision to move to a two-dose regimen in ongoing phase III trials, and how ChAdOx1 nCov-19 induces broad antibody and T cell functions. These findings […]
FBI: Beware of scammers selling fake COVID-19 antibody tests
(HealthDay)—Fake or unapproved COVID-19 antibody tests are being sold by scammers, the Federal Bureau of Investigation warns. The FBI said fraudsters are also trying to get people’s personal information (such as names, birthdates and Social Security numbers) as well as personal health information (including Medicare and/or private health insurance info). […]
Coronaviruses do not readily induce cross-protective antibody responses
Patients infected with either severe acute respiratory syndrome coronavirus (SARS-CoV) or SARS-CoV-2 produce antibodies that bind to the other coronavirus, but the cross-reactive antibodies are not cross protective, at least in cell-culture experiments, researchers report May 17 in the journal Cell Reports. It remains unclear whether such antibodies offer cross […]