Patients with colorectal cancer (CRC) who are also obese have a poorer survival than those who are not obese. A new study suggests that they may be receiving a lower cumulative dose of adjuvant chemotherapy, and that this potential “under treatment” could be the explanation for the worse outcomes. The […]
NEW YORK (Reuters Health) – Trastuzumab deruxtecan, an antibody-drug conjugate, showed “promising and durable activity” in HER2-positive metastatic colorectal cancer (CRC) refractory to standard treatment in an open-label phase-2 trial. HER2 amplification is seen in 2% to 3% of colorectal tumors, but there are currently no approved HER2-targeted therapies for […]
Consumption of ultra-processed foods and drink could increase the risk of developing colorectal cancer. This was the conclusion of a large study undertaken by the Barcelona Institute for Global Health (ISGlobal), a center supported by the "la Caixa" Foundation, based on questionnaires about food behaviors completed by around 8,000 people […]
NEW YORK (Reuters Health) – Contrary to previous reports, primary tumor resection prior to chemotherapy did not confer a survival benefit in colorectal cancer patients in a randomized phase 3 study in Japan. “I was surprised by the findings because we designed the study to test the superiority of primary […]