Huntington’s disease is a genetic neurodegenerative disorder caused by mutations in the protein huntingtin and characterized by involuntary dance-like movements, severe behavioral changes and cognitive impairment. That neuronal traffic is impaired in this disease has been very well known for several years. But that this deranged trafficking could be ameliorated […]
New research from the UVA Cancer Center could rescue once-promising immunotherapies for treating solid cancer tumors, such as ovarian, colon and triple-negative breast cancer, that ultimately failed in human clinical trials. The research from UVA’s Jogender Tushir-Singh explains why antibody approaches effectively killed cancer tumors in lab tests, but proved […]
Taking progestogens—steroid hormones—during pregnancy could reduce the risk of preterm birth in high-risk single baby pregnancies, research has shown. Although these compounds have been in use for some time, results of individual clinical trials investigating their effectiveness in preventing preterm birth have been conflicting, and so further evaluation of the […]
Researchers at the University of Alabama at Birmingham have identified a new molecular target that could potentially treat the deadly, aging-related lung disease idiopathic pulmonary fibrosis (IPF). The study, which will be published March 10 in the Journal of Experimental Medicine (JEM), suggests that targeting a protein called MDM4 could prevent […]
Scientists don’t know exactly what percentage of the population will need to get a COVID vaccine to achieve herd immunity. Some diseases, such as whooping cough, need very high rates of vaccination between 90-95%. The rise of new, more infectious coronavirus variants might mean even more people may need to […]
A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. The findings appear in the March issue […]
When we tear a muscle ” stem cells within it repair the problem. We can see this occurring not only in severe muscle wasting diseases such as muscular dystrophy and in war veterans who survive catastrophic limb injuries, but also in our day to day lives when we pull a […]
Universal HIV testing with linkage to treatment and prevention may be a promising approach to accelerate reductions in new infections in generalized epidemic settings, according to a study published February 9th, 2021 in the open-access journal PLOS Medicine by Catherine Koss of the University of California, San Francisco, and colleagues. […]
Nearly one in three working-age adults in France (29%) surveyed in July 2020—when lockdown restrictions had been eased—were outright opposed to being vaccinated against the virus, according to new research published in The Lancet Public Health journal. Researchers found that more than two-thirds of people (71%) could accept a vaccine […]
In the fight against severe diseases like cancer, patients often endure a discomforting, weekslong gap between when treatment begins and when doctors can tell if it’s working. The problem often stems from an inability to track the disease’s progression in anything close to real time. Now Glympse Bio, a startup […]