I still remember the feeling of the first joint: I was so calm, relaxed and at ease with the world around me. A few weeks later, I took speed in my local park, with a crowd of older boys from the estate I lived on. This made me feel really […]
Some FDA-approved drugs could be repurposed to treat people infected with COVID-19
Despite the development of SARS-CoV-2 vaccines, effective therapeutics are needed until worldwide immunity has been achieved. A study published in PLOS Pathogens by Adam Pickard and Karl Kadler at University of Manchester, United Kingdom, and colleagues suggests that some FDA-approved drugs could be safely repurposed to treat COVID-19 infections. The […]
Study paves the way to a new drug design concept
Hydrogen peroxide reacts with copper to produce hydroxyl radicals with strong antibacterial properties. However, this requires high copper concentrations because two copper atoms have to come close together, which occurs by chance. Now, scientists at Tokyo University of Science, Japan, engineered a long polymer with copper-containing side units that create […]
Researchers discover a molecular pathway that triggers fatal cardiac atrophy
In many situations, heart muscle cells do not respond to external stresses in the same ways that skeletal muscle cells do. But under some conditions, heart and skeletal muscles can both waste away at fatally rapid rates, according to a new study led by experts at Cincinnati Children's. The new […]
New approach targeting viral RNA could lead to broad spectrum anti-viral drugs
A new approach to tackling viruses by targeting the 'control center' in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defense against future pandemics, according to new research at the University of Birmingham. In a new study, published in Angewandte Chemie, researchers have […]
Statins improve 28-day mortality in hospitalized COVID-19 patients
Amid the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), people with comorbidities are at a higher risk of developing severe disease. In the fight against COVID-19, scientists are racing to determine effective treatments to reduce mortality among infected individuals. Now, researchers at Harvard Medical […]
Mouse monoclonal antibodies protect against SARS-CoV-2 wildtype, UK and South African variants
The importance of cross-neutralizing antibodies to the recently emerged variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is evident in light of the fact that these variants are highly transmissible as well as being able to evade immune responses to earlier variants of this virus. A new preprint […]
Novel polyclonal antibody XAV-19 efficiently neutralizes UK and South African SARS-CoV-2 variants
A promising new study, released as a preprint on the bioRxiv* server, reports on the high neutralizing efficacy of a polyclonal swine antibody against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the novel coronavirus disease 2019 (COVID-19). By demonstrating the ability of this antibody to […]
Study highlights the importance of benzothiazole in TB treatment regimens
Tuberculosis is a serious infectious disease, which is caused by the Mycobacterium tuberculosis, generally it affects the lungs. Tuberculosis is spread from one person to another through microscopic droplets released into the air, it can happen through coughs, speaks, sneezes, spits, laughs from the active tuberculosis patient. According to the […]
Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds
As the coronavirus disease (COVID-19) pandemic continues, scientists race to develop or find effective treatments to stem its spread. At the same time, health experts and scientists continue to determine which existing drugs could be repurposed to treat COVID-19. Researchers at the University of Hong Kong found that Clofazimine, a […]