Study paves the way to a new drug design concept

Hydrogen peroxide reacts with copper to produce hydroxyl radicals with strong antibacterial properties. However, this requires high copper concentrations because two copper atoms have to come close together, which occurs by chance. Now, scientists at Tokyo University of Science, Japan, engineered a long polymer with copper-containing side units that create […]

Statins improve 28-day mortality in hospitalized COVID-19 patients

Amid the coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), people with comorbidities are at a higher risk of developing severe disease. In the fight against COVID-19, scientists are racing to determine effective treatments to reduce mortality among infected individuals. Now, researchers at Harvard Medical […]

Mouse monoclonal antibodies protect against SARS-CoV-2 wildtype, UK and South African variants

The importance of cross-neutralizing antibodies to the recently emerged variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is evident in light of the fact that these variants are highly transmissible as well as being able to evade immune responses to earlier variants of this virus. A new preprint […]

Novel polyclonal antibody XAV-19 efficiently neutralizes UK and South African SARS-CoV-2 variants

A promising new study, released as a preprint on the bioRxiv* server, reports on the high neutralizing efficacy of a polyclonal swine antibody against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the novel coronavirus disease 2019 (COVID-19). By demonstrating the ability of this antibody to […]

Clofazimine inhibits coronaviruses including SARS-CoV-2, study finds

As the coronavirus disease (COVID-19) pandemic continues, scientists race to develop or find effective treatments to stem its spread. At the same time, health experts and scientists continue to determine which existing drugs could be repurposed to treat COVID-19. Researchers at the University of Hong Kong found that Clofazimine, a […]