In a clinical trial of 113 patients led by researchers at Imperial College London and UCL, retinal imaging technology called Detection of Apoptosis in Retinal Cells (DARC) was able to identify areas of the eye that were showing signs of geographic atrophy (GA) – a common condition that causes reduced […]
A modelling toolkit to predict local COVID-19 impact
A Sussex team—including university mathematicians—have created a new modeling toolkit which predicts the impact of COVID-19 at a local level with unprecedented accuracy. The details are published in the International Journal of Epidemiology, and are available for other local authorities to use online, just as the UK looks as though […]
How to predict severe influenza in hospitalized patients
Published today in Nature Communications, the team from the Peter Doherty Institute for Infection and Immunity (Doherty Institute), Alfred Health and Monash University sought to understand which patients would recover quickly from influenza and which would become severely ill. The four-year project took samples from patients hospitalized with influenza at […]
AI analytics predict COVID-19 patients’ daily trajectory in UK intensive care
Researchers used AI to identify which daily changing clinical parameters best predict intervention responses in critically ill COVID-19 patients. The investigators used machine learning to predict which patients might get worse and not respond positively to being turned onto their front in intensive care units (ICUs) – a technique known […]
Level of chromosomal abnormality in lung cancer may predict immunotherapy response
Patients with non-small cell lung cancer (NSCLC) whose cancer cells have low levels of aneuploidy—an abnormal number of chromosomes—tend to respond better to immune checkpoint inhibitor drugs than patients with higher levels, Dana-Farber Cancer Institute researchers will report at the virtual AACR Annual Meeting 2021. In analyzing data from hundreds […]
Online search activity can help predict peaks in COVID-19 cases
Analyzing internet search activity is an established method of tracking and understanding infectious diseases, and is currently used to monitor seasonal flu. The new findings show that online search data can be used with more established approaches to develop public health surveillance methods for novel infectious diseases as well. For […]
CTC dynamics may predict treatment response/prognosis in metastatic breast cancer patients
Early circulating tumor cell dynamics were associated with overall survival in patients with metastatic breast cancer, according to a meta-analysis presented at the 2020 San Antonio Breast Cancer Symposium, held Dec. 8-11. “With the increasing number of treatment options available to patients with metastatic breast cancer, being able to predict […]
Blood test may accurately predict Alzheimer’s: study
Scientists said Monday they had developed a way of predicting if patients will develop Alzheimer’s disease by analysing their blood, in what experts hailed as a potential “gamechanger” in the fight against the debilitating condition. Around 50 million people live with Alzheimer’s, a degenerative brain disease that accounts for more […]