There are many components to aging, both mental and physical. When it comes to the infrastructure of the human body—the musculoskeletal system that includes muscles, bones, tendons and cartilage—age-associated decline is inevitable, and the rate of that decline increases the older we get. The loss of muscle function—and often muscle […]
Scientists identify promising immunotherapy combination for pediatric brain cancer
Scientists at Sanford Burnham Prebys have discovered that combining immunotherapy with a drug called tumor necrosis factor (TNF) eradicated a deadly type of pediatric brain tumor in mice. The discovery, published in Nature Neuroscience, is expected to lead to a clinical trial to test the benefits of the treatment in […]
Osteoarthritis research in progeria mouse models reveals promising treatment combinations
Hutchinson-Gilford progeria syndrome (HGPS) is a fatal condition that is especially prevalent in the skin, cardiovascular and the musculoskeletal systems. There exists a wide gap between existing knowledge of the disease and a potential treatment or cure. In a study published today in the journal Proceedings of the National Academy […]