New versatile genetic test for lymphoid neoplasms supports personalized management of patients

Increasing knowledge about genomic biomarkers has facilitated better monitoring and personalized management of patients with B-cell malignant tumors. A new integrative, capture-based, next-generation sequencing (NGS) panel, LYmphoid NeXt-Generation Sequencing (LYNX), can detect and analyze standard and novel biomarkers in the most common lymphoid neoplasms simultaneously. This represents a crucial step […]

A simple blood test to identify patients at risk of nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and can progress to liver cirrhosis, liver failure or cancer. Currently, nonalcoholic steatohepatitis (NASH) diagnosis requires an invasive liver biopsy which can lead to procedural complications. Now, researchers at Osaka University working with international collaborators have identified a […]

Researchers synthesize and test the anti-HIV activity of CD4-mimicking molecules

A team of scientists led by the Institute of Biomaterials and Bioengineering at Tokyo Medical and Dental University (TMDU) have created novel molecules that prevent human immunodeficiency virus (HIV) particles from attacking immune cells. This is accomplished by injecting compounds mimicking the protein the virus usually uses to enter the […]

New test to help fight deadly melanoma

Researchers from QIMR Berghofer Medical Research Institute have developed a prototype test that can help identify if patients with deadly metastasised melanoma are likely to benefit from immunotherapy. Details about the test and the study are being published in Clinical Cancer Research, a journal of the American Association for Cancer […]

SARS-CoV-2 antibody test helps select donor blood samples for therapeutic use

Researchers have developed and applied a robust, versatile antibody test to assist health authorities in managing the coronavirus disease 2019 (COVID-19) pandemic, according to a study published January 14 in the open-access journal PLOS Pathogens by Andrea Gamarnik of the Fundación Instituto Leloir-CONICET in Argentina, and colleagues. As of November […]