In a clinical trial of 113 patients led by researchers at Imperial College London and UCL, retinal imaging technology called Detection of Apoptosis in Retinal Cells (DARC) was able to identify areas of the eye that were showing signs of geographic atrophy (GA) – a common condition that causes reduced […]
New versatile genetic test for lymphoid neoplasms supports personalized management of patients
Increasing knowledge about genomic biomarkers has facilitated better monitoring and personalized management of patients with B-cell malignant tumors. A new integrative, capture-based, next-generation sequencing (NGS) panel, LYmphoid NeXt-Generation Sequencing (LYNX), can detect and analyze standard and novel biomarkers in the most common lymphoid neoplasms simultaneously. This represents a crucial step […]
A simple blood test to identify patients at risk of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and can progress to liver cirrhosis, liver failure or cancer. Currently, nonalcoholic steatohepatitis (NASH) diagnosis requires an invasive liver biopsy which can lead to procedural complications. Now, researchers at Osaka University working with international collaborators have identified a […]
Researchers synthesize and test the anti-HIV activity of CD4-mimicking molecules
A team of scientists led by the Institute of Biomaterials and Bioengineering at Tokyo Medical and Dental University (TMDU) have created novel molecules that prevent human immunodeficiency virus (HIV) particles from attacking immune cells. This is accomplished by injecting compounds mimicking the protein the virus usually uses to enter the […]
Adherence to UK’s test, trace, and isolate system is low
Levels of adherence to the UK’s test, trace, and isolate system and understanding of the main symptoms of COVID-19 are low, particularly among men, younger age groups, people with a dependent child in the home, key workers, and those experiencing greater financial hardship, finds an analysis of online survey data […]
New test to help fight deadly melanoma
Researchers from QIMR Berghofer Medical Research Institute have developed a prototype test that can help identify if patients with deadly metastasised melanoma are likely to benefit from immunotherapy. Details about the test and the study are being published in Clinical Cancer Research, a journal of the American Association for Cancer […]
Study: New prostate cancer test could avoid unnecessary biopsies
A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients. The findings appear in the March issue […]
New, simplified genetic test effectively screens for hereditary cancers
Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers. This alternative to complex, multi-step testing workflows can also determine […]
SARS-CoV-2 antibody test helps select donor blood samples for therapeutic use
Researchers have developed and applied a robust, versatile antibody test to assist health authorities in managing the coronavirus disease 2019 (COVID-19) pandemic, according to a study published January 14 in the open-access journal PLOS Pathogens by Andrea Gamarnik of the Fundación Instituto Leloir-CONICET in Argentina, and colleagues. As of November […]