Developing effective treatment methods for Alzheimer’s disease has proved difficult. The most effective, which have just been approved, only provide marginal effects. There are several major reasons why they are not effective, one of which is that the antibodies used do not bind to all the types of toxic clumps […]
Patients with COPD are treated with drugs to improve the breathing ability in combination with inhaled corticosteroids to reduce the risk of acute worsening of the lung conditions. But the balance between reduced exacerbations and increased adverse effects of the drugs depends on the dose and on patient characteristics. Researchers […]
A procedure widely used to treat birth-related brain damage in newborn babies in low and middle income countries (LMICs) may increase the risk of death. This is the finding of research led by Imperial College London, together with several large hospitals in South Asia, published in the journal The Lancet […]
A research group led by Prof. Li Guohui from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS), in collaboration with Prof. Chen Jianfeng’s group from Shanghai Institute of Biochemistry and Cell Biology of CAS, revealed the regulation mechanism of integrin α4β7 mediated human immunodeficiency […]
Patients with Achilles tendinopathy, a disease of the Achilles tendon that can potentially cause significant pain, receive no benefit from being treated with platelet rich plasma (PRP) injection, a clinical trial led by the University of Warwick has found. PRP is a treatment often used for a number of orthopaedic […]
Scientists from the Hackensack Meridian Center for Discovery and Innovation, working with collaborators from across the globe, uncovered the mechanism of action of a novel anti-tuberculosis drug that they have helped develop. The new findings show how the enzyme inhibitor triaza-coumarin, or TA-C, is metabolized by the TB germs, which […]
Disparities exist in the treatment of people with headache disorders because of race and ethnicity, socioeconomic status and geography, according to a review article published in the June 9, 2021, online issue of Neurology. The article, developed by 16 headache experts, reviews the existing research on headache and health care […]
India is currently fighting its second wave of COVID-19 while cases of rare and often fatal fungal disease mucormycosis are beginning to soar alongside this second surge of COVID cases. The infection, which has high mortality rates, is threatening the health of those across India where many regions are already […]
Targeting a specific cancer survival gene in colorectal cancer could lead to new treatment options for advanced disease, new research suggests. Researchers from the Wellcome Sanger Institute, in collaboration with the Candiolo Cancer Institute in Italy and the Netherlands Cancer Institute, used state-of-the-art patient derived organoid models to gather information […]
In a comprehensive analysis of human gene activation data, researchers from the Centenary Institute have discovered that the dipeptidyl peptidase-4 (DPP4) gene family is strongly implicated in the development of human hepatocellular carcinoma (HCC), the most common type of primary liver cancer. Reported in the journal Cancers, the research suggests […]