Intranasal COVID-19 vaccine candidate shows sterilizing immunity in preclinical tests

University of Alabama at Birmingham researchers report additional preclinical evidence of the potency of a single-dose, intranasal COVID-19 vaccine candidate—AdCOVID—that was created by Altimmune Inc., a Maryland-based clinical-stage biopharmaceutical company. The UAB researchers, led by Fran Lund, Ph.D., in collaboration with Altimmune, have found that a single intranasal dose provided […]

French-Austrian COVID vaccine in last trial stage

French-Austrian vaccine developer Valneva on Wednesday announced that it had launched a Phase 3 trial of its candidate vaccine against COVID-19—the last testing stage before seeking regulatory approval. The study, which has been dubbed “Cov-Compare”, will compare how participants’ immune systems respond to Valneva’s VLA2001 vaccine with how they respond […]

J&J Vaccine Reviewed for Links to More Reports of Side Effects

(Reuters) – The United States is reviewing reports of a handful of potential cases of severe side effects among people who received Johnson & Johnson’s COVID-19 vaccine in addition to those that led to a pause in its use, a top U.S. public health official said on Monday. U.S. health […]

How Three Families Enrolled Their Kids in COVID-19 Vaccine Trials

Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. As more and more adults are getting vaccinated against COVID-19, researchers are reaching out to families as they recruit the youngest members of the population to test how effective the vaccine will be in them. For […]

Journalists Unpack Patchwork Vaccine Rollout, Rapid Covid Tests and More

California Healthline correspondent Rachel Bluth unpacked California’s newly expanded vaccine eligibility rules and the state’s vaccine appointment website on KALW’s “Your Call” on Thursday. Click here to hear Bluth on KALW California Healthline correspondent Angela Hart discussed California cities’ experiment with city-managed homeless camps on KQED’s “Forum” on Thursday. Click […]

COVID-19 Vaccine Response Lower in Kidney Dialysis Patients

Most patients who are receiving maintenance hemodialysis develop a good antibody response after being given two doses of the Pfizer-BioNTech COVID-19 vaccine, but their responses are still significantly lower than those of healthcare workers who do not have kidney disease, the first study of its kind shows. “It is well […]